What: UFC 321
Who: Tom Aspinall (c) vs Ciryl Gane for the UFC heavyweight title; Virna Jandiroba (c) vs Mackenzie Dern for the UFC ladies’s strawweight title
The place: Etihad Area, Abu Dhabi, United Arab Emirates
When: Saturday, October 25, 4:30 p.m. EDT
Watch: TNT Sports activities Field Workplace
A pair of title bouts are headlining the UFC 321 card. Champion Tom Aspinall will probably be seeking to retain the UFC heavyweight title belt in opposition to Ciryl Gane in the primary occasion on this card.
It is the champ Aspinall who oddsmakers are setting because the stable -390 favourite within the UFC betting traces. You will get +295 underdog odds should you choose to again the challenger Gane on this betting market.
Gane is the No. 1 contender within the UFC heavyweight rankings. Aspinall was just lately upgraded from interim heavyweight champion to undisputed heavyweight champion.
Let us take a look at the newest betting traces. Odds are topic to alter.
The co-main occasion is a title bout for the vacant ladies’s strawweight belt between prime contenders Virna Jandiroba and Mackenzie Dern. It is Dern who’s established because the -160 favourite to win the combat.
On this article, OSB will probably be analyzing the fighters in every of those fundamental occasion bouts, providing a predicted winner in each matchups, and in addition offering some further notes and knowledge relating to UFC 321 picks and UFC betting.
UFC 321 Overview: Tom Aspinall vs Ciryl Gane
England’s Aspinall (15-3) gained the interim heavyweight title in 2023 through a knockout of Sergei Pavlovich at UFC 295.
The brand new era of heavyweights 💪#UFC321 | Saturday, Primetime | LIVE on TNT Sports activities Field Workplace pic.twitter.com/pEMTnI3xhO
— UFC on TNT Sports activities (@ufcontnt) October 23, 2025
In 15 profession bouts, French fighter Gane (13-2) has suffered his solely losses by the hands of UFC heavyweight champions Jon Jones and Francis Ngannou.
Fighter Highlight: Tom Aspinall
He defended the belt with a KO of Curtis Blaydes at UFC 304. Shortly thereafter, Aspinall was given the improve to undisputed heavyweight champ.
The win over Blaydes avenged Aspinall’s 2022 TKO loss to the identical fighter. At 5.18, Aspinall owns the most important placing differential in UFC historical past. None of his 18 profession MMA bouts have ever gone the space. Aspinall was named Breakthrough Fighter of the 12 months on the 2024 World MMA Awards.
Fighter Highlight: Ciryl Gane
Gane gained the UFC interim heavyweight title with a victory over Derrick Lewis at UFC 265 in 2021. However he was overwhelmed by Ngannou in his subsequent bout.
As the highest contender within the heavyweight division, Gane has defeated a number of ranked fighters. His combat card reveals two wins over No. 2 Alexander Volkov, in addition to victories over Serghei Spivac (No. 7), Lewis (No. 8), and Tai Tuivasa (No. 10).
Prediction: These are two very athletic fighters who deliver contrasting types contained in the octagon. Very cellular contained in the cage, Aspinall’s mixture of agility and energy permits him to dominate opponents and overwhelm them. His report reveals seven first-round stoppages, with simply considered one of Aspinall’s UFC fights reaching the second spherical.
Tom Aspinall
To defeat Ciryl Gane at UFC 321
-390
That is all dangerous information for Gane. He historically struggles in opposition to fighters who can strike powerfully and grapple successfully. Gane would be the most technical striker that Aspinall has confronted. However the Frenchman wants to remain on his toes to win. His underwhelming floor recreation will show Gane’s undoing.
UFC 321 Overview: Virna Jandiroba vs Mackenzie Dern
These two fighters met 5 years in the past on the undercard of UFC 256. Dern gained the bout by unanimous determination.
Fighter Highlight: Virna Jandiroba
The previous Invicta FC ladies’s strawweight champion, Jandiroba (22-3), is using a five-fight successful streak. She’s 6-1 since that loss to Dern.
4 of her 5 wins throughout this streak have been unanimous determination victories. The ???? is the No. 1 contender within the UFC ladies’s strawweight division.
Fighter Highlight: Mackenzie Dern
Born within the USA to a Brazilian father, Dern (15-5), spent a lot of her formative years going backwards and forwards between the 2 nations. She was a world champion in that sport.
Shifting into MMA, Dern was 10-1 following her win over Jandiroba. Nonetheless, she’s simply 5-4 since that bout.
Prediction: These are two veterans of the cage. Jandiroba is 37 and Dern is 35. Each have backgrounds in Brazilian jiu-jitsu, every holding black belts within the self-discipline.
Mackenzie Dern
To defeat Virna Jandirona at UFC 321
-160
Their first assembly was an in depth name that went the space, and you need to anticipate the same end result to this bout. It’s going to go the space. The distinction will probably be when each fighters are upright. It is mainly a break-even state of affairs between Dern and Jandiroba on the subject of grappling.
Mackenzie Dern at UFC 321 press convention 🇧🇷 pic.twitter.com/imH6Gko3Gl
— Cage Bites MMA (@CageBites) October 23, 2025
The place the slight edge goes to Dern is in placing energy. So long as she would not go away herself open to a Jandiroba counter punch, search for Dern to take the shut determination on the judges’ scorecards.
Enhance Your UFC Picks
Earlier than getting your wagers down on UFC 321, remember to take a look at the greatest UFC betting odds to make sure you are getting the most effective bets obtainable. You may also use sportsbooks critiques 2025 to discover a betting website to service your wants in UFC betting picks. And should you’re new to the world of on-line sports activities betting, do not fret about being in over your head. There are many how-to ideas that you could peruse in our helpful sports activities betting information.
