The 49ers are 7-point house favorites over the Panthers on Monday Evening Soccer
Carolina’s protection ranks thirty first in stress charge this season
See my Panthers vs 49ers predictions and picks under, plus the newest unfold for Monday Evening Soccer
A pair of playoff hopefuls conflict on Monday Evening Soccer because the Panthers (6-5, 3-3 away) go to the 49ers (7-4, 2-2 house). Brock Purdy made a profitable return to the San Fran lineup final week in a blowout win over Arizona, and on-line sportsbooks predict one other convincing victory versus Carolina per the MNF odds.
Kickoff is scheduled for 8:15pm ET / 5:15pm PT from Levi’s Stadium, in Santa Clara, CA, with ESPN offering the printed protection.
Under, you’ll discover my Panthers vs 49ers predictions and picks, plus the newest unfold for Monday Evening Soccer.
Panthers vs 49ers Predictions and Picks
San Francisco 49ers -7.0 (-120) at bet365
Neither certainly one of these groups has actual upside within the Tremendous Bowl 60 odds, however I feel the market is somewhat gentle on the Niners on this spot. I’m comfy laying 7 factors in my Panthers vs 49ers picks, as I anticipate San Fran to have the ability to do no matter they need on offense.
Let’s begin with Purdy. He threw 3 TD in first recreation again from damage, and will have on a regular basis on this planet to carve up a Carolina protection whose move rush is non-existent. They rank bottom-three in move rush win charge and EPA/move, and thirty first in stress charge.
Purdy in a clear pocket is a harmful proposition, and the numbers naked that out. Final season, Purdy posted an 84.5 passing grade when saved clear, averaging 9.3 yards per try, with a 71% completion charge. Below stress, his completion proportion dropped to 53.6%, whereas his passing grade plummeted by 30 factors.
Carolina Panthers Defensive Stats
Additionally working in his favor, is the improved well being of San Fran’s move catchers. Each George Kittle and Ricky Pearsall are again from damage, leaving Brandon Aiyuk as the one beginning ability place participant lacking from their roster. Kittle has caught 15 passes and three TD in final two video games, and now faces a Carolina protection that’s allowed the fifth most manufacturing to enemy tight ends.
Sticking with San Fran, that is additionally a revenge recreation for Christian McCaffrey. He’ll face his former workforce for the primary time since being traded in 2022, and attracts a really favorable matchup. McCaffrey leads the NFL in scrimmage yards, whereas the Panthers rank bottom-eight in working again manufacturing allowed.
On the opposite facet of the ball, Carolina has been a little bit of a college yard bully this season. Versus groups outdoors the playoff image they’re averaging 23 factors per recreation. In opposition to groups at the moment projected for the postseason, that quantity shrinks to 11.25 factors per recreation.
The Niners protection has been decimated by damage in 2025, with the move rush taking the largest hit. With out Nick Bosa and Fred Warner they’ve struggled to generate stress, however that shouldn’t be an enormous deal towards Bryce Younger.
The previous primary choose has performed simply as poorly from a clear pocket this season as he has underneath duress. Younger’s passing grade solely falls from 65.3 to 60.1 when the warmth is on, and he’s truly dedicated extra turnover worthy performs from a clear pocket (6) than he has underneath stress (5).
Younger is coming off among the finest video games of his profession, however that was indoors versus the dreadful Falcons. He’s posted passing grades of 37.6 and 51.9 in his final two out of doors video games versus playoff worthy competitors, with just one large time throw.
CAR Panthers vs SF 49ers Level Unfold
Earlier than making any Monday Evening Soccer wager, be sure you seek the advice of one of the best soccer betting apps. As of Sunday, one of the best guide to guess San Fran -7 is at Bbet365. That wager is out there at -120 odds, whereas nearly all of the opposite business books have moved the road to Niners -7.5.
Whole-wise, the over/underneath is painted 49.5 at most on-line sportsbooks, and that’s a quantity that six of the Panthers final seven out of doors video games have did not exceed.
Per the NFL public betting percentages, San Fran -7 is attracting nearly all of the unfold motion. That facet of the unfold is accounting for 62% of the ATS bets, and 54% of the deal with.
Odds as of Nov. 23. New clients can declare the FanDuel promo code and get a bonus to guess on MNF.
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